Effect of aflatoxins on rat peritoneal macrophages.

نویسندگان

  • V Cusumano
  • G B Costa
  • S Seminara
چکیده

Phagocytosis, intracellular killing of Candida albicans, and superoxide production by rat peritoneal macrophages exposed to aflatoxins B1, B2, G1, G2, B2a, and M1 at several times and concentrations were analyzed to evaluate the intensity of a depressive effect for each mycotoxin. All aflatoxins used at very low concentrations had a depressive effect on the functions of macrophages. The biggest impairment of phagocytosis, intracellular killing, and spontaneous superoxide production was observed in macrophages exposed to aflatoxins B1 and M1.

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عنوان ژورنال:
  • Applied and environmental microbiology

دوره 56 11  شماره 

صفحات  -

تاریخ انتشار 1990